Initial Pulmonary Respiration Causes Massive Diaphragm Damage and Hyper-CKemia in Duchenne Muscular Dystrophy Dog

The molecular mechanism of muscle degeneration in a lethal muscle disorder Duchene muscular dystrophy (DMD) has not been fully elucidated. The dystrophic dog, a model of DMD, shows a high mortality rate with a marked increase in serum creatine kinase (CK) levels in the neonatal period. By measuring...

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Autores principales: Nakamura, Akinori, Kobayashi, Masanori, Kuraoka, Mutsuki, Yuasa, Katsutoshi, Yugeta, Naoko, Okada, Takashi, Takeda, Shin'ichi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711052/
https://ncbi.nlm.nih.gov/pubmed/23851606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02183
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