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Mammalian Models of Duchenne Muscular Dystrophy: Pathological Characteristics and Therapeutic Applications
Duchenne muscular dystrophy (DMD) is a devastating X-linked muscle disorder characterized by muscle wasting which is caused by mutations in the DMD gene. The DMD gene encodes the sarcolemmal protein dystrophin, and loss of dystrophin causes muscle degeneration and necrosis. Thus far, therapies for t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3022202/ https://ncbi.nlm.nih.gov/pubmed/21274260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/184393 |
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