5-Lipoxygenase Metabolite 4-HDHA Is a Mediator of the Antiangiogenic Effect of ω-3 Polyunsaturated Fatty Acids

Lipid signaling is dysregulated in many diseases with vascular pathology, including cancer, diabetic retinopathy, retinopathy of prematurity, and age-related macular degeneration. We have previously demonstrated that diets enriched in ω-3 polyunsaturated fatty acids (PUFAs) effectively reduce pathol...

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Detalhes bibliográficos
Main Authors: Sapieha, Przemyslaw, Stahl, Andreas, Chen, Jing, Seaward, Molly R., Willett, Keirnan L., Krah, Nathan M., Dennison, Roberta J., Connor, Kip M., Aderman, Christopher M., Liclican, Elvira, Carughi, Arianna, Perelman, Dalia, Kanaoka, Yoshihide, SanGiovanni, John Paul, Gronert, Karsten, Smith, Lois E. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711031/
https://ncbi.nlm.nih.gov/pubmed/21307302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3001571
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