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Rapid Glucocorticoid Receptor Exchange at a Promoter Is Coupled to Transcription and Regulated by Chaperones and Proteasomes

Exchange of the glucocorticoid receptor (GR) at promoter target sites provides the only known system in which transcription factor cycling at a promoter is fast, occurring on a time scale of seconds. The mechanism and function of this rapid exchange are unknown. We provide evidence that proteasome a...

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Auteurs principaux: Stavreva, Diana A., Müller, Waltraud G., Hager, Gordon L., Smith, Carolyn L., McNally, James G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC371101/
https://ncbi.nlm.nih.gov/pubmed/15024059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.7.2682-2697.2004
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