Recruitment of the SWI-SNF Chromatin Remodeling Complex as a Mechanism of Gene Activation by the Glucocorticoid Receptor τ1 Activation Domain

The SWI-SNF complex has been shown to alter nucleosome conformation in an ATP-dependent manner, leading to increased accessibility of nucleosomal DNA to transcription factors. In this study, we show that the SWI-SNF complex can potentiate the activity of the glucocorticoid receptor (GR) through the...

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Bibliographic Details
Main Authors: Wallberg, Annika E., Neely, Kristen E., Hassan, Ahmed H., Gustafsson, Jan-Åke, Workman, Jerry L., Wright, Anthony P. H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110817/
https://ncbi.nlm.nih.gov/pubmed/10688647
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