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PHF10 Is Required for Cell Proliferation in Normal and SV40-Immortalized Human Fibroblast Cells
Normal human diploid fibroblasts have limited life span in culture and undergo replicative senescence after 50–60 population doublings. On the contrary, cancer cells typically divide indefinitely and are immortal. Expression of SV40 large T and small t antigens in human fibroblasts transiently exten...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
S. Karger AG
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711003/ https://ncbi.nlm.nih.gov/pubmed/20068294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000251960 |
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