Src Family Kinase Inhibitor PP2 Has Different Effects on All-Trans-Retinoic Acid or Arsenic Trioxide-Induced Differentiation of an Acute Promyelocytic Leukemia Cell Line

PURPOSE: Leukemic promyelocytes have the unique ability to undergo differentiation after exposure to retinoic acid and both differentiation and apoptosis after exposure to arsenic trioxide (ATO). Recent studies have shown that inhibition of Src family kinases (SFKs) resulted in enhancement of retino...

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Detalhes bibliográficos
Main Authors: Yoon, Suk-Gu, Cheong, Hee-Jeong, Kim, Sook-Ja, Kim, Kyoung Ha, Lee, Sang-Cheol, Lee, Namsu, Park, Hee Sook, Won, Jong-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Cancer Association 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710962/
https://ncbi.nlm.nih.gov/pubmed/23864846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2013.45.2.126
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