ΔFosB Induces Osteosclerosis and Decreases Adipogenesis by Two Independent Cell-Autonomous Mechanisms

Osteoblasts and adipocytes may develop from common bone marrow mesenchymal precursors. Transgenic mice overexpressing ΔFosB, an AP-1 transcription factor, under the control of the neuron-specific enolase (NSE) promoter show both markedly increased bone formation and decreased adipogenesis. To determ...

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Detalhes bibliográficos
Main Authors: Kveiborg, Marie, Sabatakos, George, Chiusaroli, Riccardo, Wu, Meilin, Philbrick, William M., Horne, William C., Baron, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371096/
https://ncbi.nlm.nih.gov/pubmed/15024071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.7.2820-2830.2004
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