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Permeation rates of penicillins indicate that Escherichia coli porins function principally as nonspecific channels
Small, hydrophilic compounds such as β-lactams diffuse across the outer membrane of Gram-negative bacteria through porin channels, which were originally thought to be nonspecific channels devoid of any specificity. However, since the discovery of an ampicillin-binding site within the OmpF channel in...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710850/ https://ncbi.nlm.nih.gov/pubmed/23798411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310333110 |
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