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Permeation rates of penicillins indicate that Escherichia coli porins function principally as nonspecific channels

Small, hydrophilic compounds such as β-lactams diffuse across the outer membrane of Gram-negative bacteria through porin channels, which were originally thought to be nonspecific channels devoid of any specificity. However, since the discovery of an ampicillin-binding site within the OmpF channel in...

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Detalhes bibliográficos
Main Authors: Kojima, Seiji, Nikaido, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710850/
https://ncbi.nlm.nih.gov/pubmed/23798411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310333110
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