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Preextinction Viral RNA Can Interfere with Infectivity

When the error rate during the copying of genetic material exceeds a threshold value, the genetic information cannot be maintained. This concept is the basis of a new antiviral strategy termed lethal mutagenesis or virus entry into error catastrophe. Critical for its success is preventing survival o...

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Autori principali: González-López, Claudia, Arias, Armando, Pariente, Nonia, Gómez-Mariano, Gema, Domingo, Esteban
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC371084/
https://ncbi.nlm.nih.gov/pubmed/15016853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3319-3324.2004
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