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Decorin causes autophagy in endothelial cells via Peg3

Soluble decorin affects the biology of several receptor tyrosine kinases by triggering receptor internalization and degradation. We found that decorin induced paternally expressed gene 3 (Peg3), an imprinted tumor suppressor gene, and that Peg3 relocated into autophagosomes labeled by Beclin 1 and m...

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Autors principals: Buraschi, Simone, Neill, Thomas, Goyal, Atul, Poluzzi, Chiara, Smythies, James, Owens, Rick T., Schaefer, Liliana, Torres, Annabel, Iozzo, Renato V.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710796/
https://ncbi.nlm.nih.gov/pubmed/23798385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305732110
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