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Limiting factors in atomic resolution cryo electron microscopy: No simple tricks

To bring cryo electron microscopy (cryoEM) of large biological complexes to atomic resolution, several factors – in both cryoEM image acquisition and 3D reconstruction – that may be neglected at low resolution become significantly limiting. Here we present thorough analyses of four limiting factors:...

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Bibliographic Details
Main Authors: Zhang, Xing, Zhou, Z. Hong
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710782/
https://ncbi.nlm.nih.gov/pubmed/21627992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2011.05.004
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