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Limiting factors in atomic resolution cryo electron microscopy: No simple tricks
To bring cryo electron microscopy (cryoEM) of large biological complexes to atomic resolution, several factors – in both cryoEM image acquisition and 3D reconstruction – that may be neglected at low resolution become significantly limiting. Here we present thorough analyses of four limiting factors:...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710782/ https://ncbi.nlm.nih.gov/pubmed/21627992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2011.05.004 |
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