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Coupling of Human Immunodeficiency Virus Type 1 Fusion to Virion Maturation: a Novel Role of the gp41 Cytoplasmic Tail

Retrovirus particles are not infectious until they undergo proteolytic maturation to form a functional core. Here we report a link between human immunodeficiency virus type 1 (HIV-1) core maturation and the ability of the virus to fuse with target cells. Using a recently developed reporter assay of...

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Detalhes bibliográficos
Main Authors: Wyma, Donald J., Jiang, Jiyang, Shi, Jiong, Zhou, Jing, Lineberger, Janet E., Miller, Michael D., Aiken, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371074/
https://ncbi.nlm.nih.gov/pubmed/15016865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3429-3435.2004
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