Apoptosis Induced by Tanshinone IIA and Cryptotanshinone Is Mediated by Distinct JAK/STAT3/5 and SHP1/2 Signaling in Chronic Myeloid Leukemia K562 Cells

Though tanshinone IIA and cryptotanshinone possess a variety of biological effects such as anti-inflammatory, antioxidative, antimetabolic, and anticancer effects, the precise molecular targets or pathways responsible for anticancer activities of tanshinone IIA and cryptotanshinone in chronic myeloi...

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Detalhes bibliográficos
Main Authors: Jung, Ji Hoon, Kwon, Tae-Rin, Jeong, Soo-Jin, Kim, Eun-Ok, Sohn, Eun Jung, Yun, Miyong, Kim, Sung-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710643/
https://ncbi.nlm.nih.gov/pubmed/23878608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/805639
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