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Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish

The study aimed to investigate the potential of zebrafish in imitating mammal phase I metabolism of natural compounds. Three diterpenoid quinones from Radix Salvia miltiorrhiza, namely tanshinone IIA (TIIA), cryptotanshinone (Cry) and tanshinone I (TI) were selected as model compounds, and their met...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wei, Yingjie, Li, Ping, Wang, Changmei, Peng, Yunru, Shu, Luan, Jia, Xiaobin, Ma, Wenquan, Wang, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269062/
https://ncbi.nlm.nih.gov/pubmed/22810195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17078617
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