Evaluation of [(11)C]MRB for assessment of occupancy of norepinephrine transporters: Studies with atomoxetine in non-human primates

[(11)C]MRB is one of the most promising radioligands used to measure brain norepinephrine transporters (NET) with positron emission tomography (PET). The objective of this study was to evaluate the suitability of [(11)C]MRB for drug occupancy studies of NET using atomoxetine (ATX), a NET uptake inhi...

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Main Authors: Gallezot, Jean-Dominique, Weinzimmer, David, Nabulsi, Nabeel, Lin, Shu-Fei, Fowles, Krista, Sandiego, Christine, McCarthy, Timothy J., Maguire, R. Paul, Carson, Richard E., Ding, Yu-Shin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710586/
https://ncbi.nlm.nih.gov/pubmed/20869448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2010.09.040
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