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Transgenic Mice Expressing the Nucleoprotein of Borna Disease Virus in either Neurons or Astrocytes: Decreased Susceptibility to Homotypic Infection and Disease

The nucleoprotein (N) of Borna disease virus (BDV) is the major target of the disease-inducing antiviral CD8 T-cell response in the central nervous system of mice. We established two transgenic mouse lines which express BDV-N in either neurons (Neuro-N) or astrocytes (Astro-N). Despite strong transg...

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Detalhes bibliográficos
Main Authors: Rauer, Mathias, Götz, Jürgen, Schuppli, Daniel, Staeheli, Peter, Hausmann, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371057/
https://ncbi.nlm.nih.gov/pubmed/15016883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3621-3632.2004
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