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RNA-methyltransferase TrmA is a dual-specific enzyme responsible for C(5)-methylation of uridine in both tmRNA and tRNA

In bacteria, trans-translation rescues stalled ribosomes by the combined action of tmRNA (transfer-mRNA) and its associated protein SmpB. The tmRNA 5′ and 3′ ends fold into a tRNA-like domain (TLD), which shares structural and functional similarities with tRNAs. As in tRNAs, the UUC sequence of the...

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Detalhes bibliográficos
Main Authors: Ranaei-Siadat, Ehsan, Fabret, Céline, Seijo, Bili, Dardel, Frédéric, Grosjean, Henri, Nonin-Lecomte, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710363/
https://ncbi.nlm.nih.gov/pubmed/23603891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.24327
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