SUMOylation alters CRMP2 regulation of calcium influx in sensory neurons

The axon/dendrite specification collapsin response mediator protein 2 (CRMP2) bidirectionally modulates N-type voltage-gated Ca(2+) channels (CaV2.2). Here we demonstrate that small ubiquitin-like modifier (SUMO) protein modifies CRMP2 via the SUMO E2-conjugating enzyme Ubc9 in vivo. Removal of a SU...

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Bibliographische Detailangaben
Hauptverfasser: Ju, Weina, Li, Qi, Wilson, Sarah M., Brittain, Joel M., Meroueh, Louay, Khanna, Rajesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710342/
https://ncbi.nlm.nih.gov/pubmed/23510938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.24224
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