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Opening Pandora’s jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders

CRMP2, also known as DPYSL2/DRP2, Unc-33, Ulip or TUC2, is a cytosolic phosphoprotein that mediates axon/dendrite specification and axonal growth. Mapping the CRMP2 interactome has revealed previously unappreciated functions subserved by this protein. Together with its canonical roles in neurite gro...

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Bibliographic Details
Main Authors: Khanna, Rajesh, Wilson, Sarah M, Brittain, Joel M, Weimer, Jill, Sultana, Rukhsana, Butterfield, Allan, Hensley, Kenneth
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539824/
https://ncbi.nlm.nih.gov/pubmed/23308041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/FNL.12.68
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