Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance

BACKGROUND: Dysregulated epidermal growth factor receptor (EGFR)-phosphoinositide-3-kinase (PI3K)-AKT signaling is considered pivotal for oral cancer, and the pathway is a potential candidate for therapeutic targeting. RESULTS: A total of 108 archival samples which were from surgically resected oral...

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Bibliografski detalji
Glavni autori: Chang, Kwang-Yu, Tsai, Shan-Yin, Chen, Shang-Hung, Tsou, Hsiao-Hui, Yen, Chia-Jui, Liu, Ko-Jiunn, Fang, Hsun-Lang, Wu, Hung-Chang, Chuang, Bin-Fay, Chou, Shao-Wen, Tang, Careen K, Liu, Shyun-Yeu, Lu, Pei-Jung, Yen, Ching-Yu, Chang, Jang-Yang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710269/
https://ncbi.nlm.nih.gov/pubmed/23806066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-43
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