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Glucose ingestion in dogs alters the hepatic extraction of insulin. In vivo evidence for a relationship between biologic action and extraction of insulin.

Oral glucose (25 g) fed to seven healthy, conscious dogs resulted in an increase in peripheral plasma glucose from 109 +/- 3 to 178 +/- 10 mg/dl. Concurrently serum insulin increased in the portal vein to levels approximately threefold greater than those in the periphery. Hepatic insulin delivery ro...

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Publicado en:J Clin Invest
Autores principales: Jaspan, J, Polonsky, K
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1982
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371007/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7037850/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110477
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