Endothelial Cells Potentiate Interferon-γ Production in a Novel Tripartite Culture Model of Human Cerebral Malaria

We have established a novel in vitro co-culture system of human brain endothelial cells (HBEC), Plasmodium falciparum parasitised red blood cells (iRBC) and peripheral blood mononuclear cells (PBMC), in order to simulate the chief pathophysiological lesion in cerebral malaria (CM). This approach has...

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Autors principals: Khaw, Loke Tim, Ball, Helen J., Golenser, Jacob, Combes, Valery, Grau, Georges E., Wheway, Julie, Mitchell, Andrew J., Hunt, Nicholas H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709908/
https://ncbi.nlm.nih.gov/pubmed/23874969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069521
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