Endothelial Cells Potentiate Interferon-γ Production in a Novel Tripartite Culture Model of Human Cerebral Malaria

We have established a novel in vitro co-culture system of human brain endothelial cells (HBEC), Plasmodium falciparum parasitised red blood cells (iRBC) and peripheral blood mononuclear cells (PBMC), in order to simulate the chief pathophysiological lesion in cerebral malaria (CM). This approach has...

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Detalhes bibliográficos
Main Authors: Khaw, Loke Tim, Ball, Helen J., Golenser, Jacob, Combes, Valery, Grau, Georges E., Wheway, Julie, Mitchell, Andrew J., Hunt, Nicholas H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709908/
https://ncbi.nlm.nih.gov/pubmed/23874969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069521
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