Endothelial Cells Potentiate Interferon-γ Production in a Novel Tripartite Culture Model of Human Cerebral Malaria

We have established a novel in vitro co-culture system of human brain endothelial cells (HBEC), Plasmodium falciparum parasitised red blood cells (iRBC) and peripheral blood mononuclear cells (PBMC), in order to simulate the chief pathophysiological lesion in cerebral malaria (CM). This approach has...

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Autores principales: Khaw, Loke Tim, Ball, Helen J., Golenser, Jacob, Combes, Valery, Grau, Georges E., Wheway, Julie, Mitchell, Andrew J., Hunt, Nicholas H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709908/
https://ncbi.nlm.nih.gov/pubmed/23874969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069521
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