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Enhancement of Residual Arylsulfatase B Activity in Feline Mucopolysaccharidosis VI by Thiol-induced Subunit Association

The molecular pathology of the deficient arylsulfatase B activity in feline mucopolysaccharidosis (MPS) VI was investigated. Compared with the highly purified normal feline hepatic enzyme, the purified MPS VI residual activity had a 100-fold higher Michaelis constant (K(m)), an altered electrophoret...

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Detalhes bibliográficos
Main Authors: Vine, Deborah T., McGovern, Margaret M., Schuchman, Edward H., Haskins, Mark E., Desnick, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC370978/
https://ncbi.nlm.nih.gov/pubmed/6799547
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