Monocyte and granulocyte-mediated tumor cell destruction. A role for the hydrogen peroxide-myeloperoxidase-chloride system.

Human monocytes stimulated with phorbol myristate acetate were able to destroy a T lymphoblast cell target (CEM). Stimulated human granulocytes were also capable of mediating CEM cytotoxicity to a comparable degree as the monocyte. CEM destruction was dependent on the pH and the effector cell number...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Weiss, S J, Slivka, A
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1982
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6276438/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110447
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