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Monocyte and granulocyte-mediated tumor cell destruction. A role for the hydrogen peroxide-myeloperoxidase-chloride system.

Human monocytes stimulated with phorbol myristate acetate were able to destroy a T lymphoblast cell target (CEM). Stimulated human granulocytes were also capable of mediating CEM cytotoxicity to a comparable degree as the monocyte. CEM destruction was dependent on the pH and the effector cell number...

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Bibliografiske detaljer
Main Authors: Weiss, S J, Slivka, A
Format: Artigo
Sprog:Inglês
Udgivet: 1982
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC370973/
https://ncbi.nlm.nih.gov/pubmed/6276438
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