MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program

Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-cell (GCB)–like and unfavorable activated B-cell (ABC)–like subtypes based on gene expression signatures. In this study, we analyzed 893 de novo DLBCL patients treated with R-CHOP (rituximab, cyclopho...

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Détails bibliographiques
Auteurs principaux: Hu, Shimin, Xu-Monette, Zijun Y., Tzankov, Alexander, Green, Tina, Wu, Lin, Balasubramanyam, Aarthi, Liu, Wei-min, Visco, Carlo, Li, Yong, Miranda, Roberto N., Montes-Moreno, Santiago, Dybkaer, Karen, Chiu, April, Orazi, Attilio, Zu, Youli, Bhagat, Govind, Richards, Kristy L., Hsi, Eric D., Choi, William W. L., Zhao, Xiaoying, van Krieken, J. Han, Huang, Qin, Huh, Jooryung, Ai, Weiyun, Ponzoni, Maurilio, Ferreri, Andrés J. M., Zhou, Fan, Slack, Graham W., Gascoyne, Randy D., Tu, Meifeng, Variakojis, Daina, Chen, Weina, Go, Ronald S., Piris, Miguel A., Møller, Michael B., Medeiros, L. Jeffrey, Young, Ken H.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2013
Sujets:
Plenary Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709650/
https://ncbi.nlm.nih.gov/pubmed/23449635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-460063
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