Single nucleotide variation in the TP53 3′ untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program

We identified multiple single nucleotide variants (SNVs) in the TP53 3′ untranslated region (3′UTR) in tumor specimens from 244 patients with diffuse large B-cell lymphoma (DLBCL). Patients carrying a wild-type TP53 coding sequence (CDS) and 1 or more 3′UTR SNVs had a better 5-year survival rate tha...

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Detalhes bibliográficos
Main Authors: Li, Yong, Gordon, Michael W., Xu-Monette, Zijun Y., Visco, Carlo, Tzankov, Alexander, Zou, Dehui, Qiu, Lugui, Montes-Moreno, Santiago, Dybkaer, Karen, Orazi, Attilio, Zu, Youli, Bhagat, Govind, Richards, Kristy L., Hsi, Eric D., Choi, William W. L., Han van Krieken, J., Huang, Qin, Ai, Weiyun, Ponzoni, Maurilio, Ferreri, Andrés J. M., Winter, Jane N., Go, Ronald S., Piris, Miguel A., Møller, Michael B., Wu, Lin, Wang, Michael, Ramos, Kenneth S., Medeiros, L. Jeffrey, Young, Ken H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668486/
https://ncbi.nlm.nih.gov/pubmed/23515929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-471722
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