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Single nucleotide variation in the TP53 3′ untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program

We identified multiple single nucleotide variants (SNVs) in the TP53 3′ untranslated region (3′UTR) in tumor specimens from 244 patients with diffuse large B-cell lymphoma (DLBCL). Patients carrying a wild-type TP53 coding sequence (CDS) and 1 or more 3′UTR SNVs had a better 5-year survival rate tha...

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Hauptverfasser: Li, Yong, Gordon, Michael W., Xu-Monette, Zijun Y., Visco, Carlo, Tzankov, Alexander, Zou, Dehui, Qiu, Lugui, Montes-Moreno, Santiago, Dybkaer, Karen, Orazi, Attilio, Zu, Youli, Bhagat, Govind, Richards, Kristy L., Hsi, Eric D., Choi, William W. L., Han van Krieken, J., Huang, Qin, Ai, Weiyun, Ponzoni, Maurilio, Ferreri, Andrés J. M., Winter, Jane N., Go, Ronald S., Piris, Miguel A., Møller, Michael B., Wu, Lin, Wang, Michael, Ramos, Kenneth S., Medeiros, L. Jeffrey, Young, Ken H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668486/
https://ncbi.nlm.nih.gov/pubmed/23515929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-471722
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