Early Preplasma Cells Define a Tolerance Checkpoint for Autoreactive B Cells()

Ab-secreting plasma cells (PCs) are the effectors of humoral immunity. In this study, we describe regulation of autoreactive B cells specific for the ribonucleoprotein Smith (Sm) at an early pre-PC stage. These cells are defined by the expression of the PC marker CD138 and normal levels of CD19 and...

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Main Authors: Culton, Donna A., O’Conner, Brian P., Conway, Kara L., Diz, Ramiro, Rutan, Jennifer, Vilen, Barbara J., Clarke, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709567/
https://ncbi.nlm.nih.gov/pubmed/16393962
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