Phenotypic Characterization of Autoreactive B Cells—Checkpoints of B Cell Tolerance in Patients with Systemic Lupus Erythematosus

DNA-reactive B cells play a central role in systemic lupus erythematosus (SLE); DNA antibodies precede clinical disease and in established disease correlate with renal inflammation and contribute to dendritic cell activation and high levels of type 1 interferon. A number of central and peripheral B...

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Bibliografiske detaljer
Main Authors: Jacobi, Annett M., Zhang, Jie, Mackay, Meggan, Aranow, Cynthia, Diamond, Betty
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685013/
https://ncbi.nlm.nih.gov/pubmed/19488401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005776
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