Loading...

The ErbB3 binding Protein EBP1 regulates ErbB2 protein levels and tamoxifen sensitivity in breast cancer cells

The ErbB2/3 heterodimer plays a critical role in breast cancer progression and in the development of endocrine resistance. EBP1, an ErbB3 binding protein, inhibits HRG-stimulated breast cancer growth, decreases ErbB2 protein levels and contributes to tamoxifen sensitivity. We report here that ectopi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lu, Yan, Zhou, Hua, Chen, Wantao, Zhang, Yuexing, Hamburger, Anne W.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709471/
https://ncbi.nlm.nih.gov/pubmed/20379846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-0873-4
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!