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Receptor-mediated regulation of superoxide production in human neutrophils stimulated by phorbol myristate acetate.

Human neutrophils contain receptors for phorbol myristate acetate (PMA), a complex lipid that induces them to generate superoxide (O (2)). Binding of PMA to these receptors displays specificity, reversibility, and high affinity. The receptor's apparent KD was approximately 0.29 nM and multiple copie...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Lehrer, R I, Cohen, L
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1981
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370927/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6271811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110378
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