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Receptor-mediated regulation of superoxide production in human neutrophils stimulated by phorbol myristate acetate.

Human neutrophils contain receptors for phorbol myristate acetate (PMA), a complex lipid that induces them to generate superoxide (O (2)). Binding of PMA to these receptors displays specificity, reversibility, and high affinity. The receptor's apparent KD was approximately 0.29 nM and multiple copie...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Lehrer, R I, Cohen, L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370927/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6271811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110378
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