Replacement therapy of alpha 1-antitrypsin deficiency. Reversal of protease-antiprotease imbalance within the alveolar structures of PiZ subjects.

The emphysema associated with the inherited serum deficiency of alpha 1-antitrypsin appears to result from an imbalance between neutrophil elastase and its major inhibitor within the alveolar structures. In the present study we assessed the feasibility of reversing this biochemical defect within the...

Full description

Saved in:
Bibliographic Details
Main Authors: Gadek, J E, Klein, H G, Holland, P V, Crystal, R G
Format: Artigo
Language:Inglês
Published: 1981
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC370909/
https://ncbi.nlm.nih.gov/pubmed/7028785
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items