Human Folliculin Delays Cell Cycle Progression through Late S and G2/M-Phases: Effect of Phosphorylation and Tumor Associated Mutations

The Birt-Hogg-Dube disease occurs as a result of germline mutations in the human Folliculin gene (FLCN), and is characterized by clinical features including fibrofolliculomas, lung cysts and multifocal renal neoplasia. Clinical and genetic evidence suggest that FLCN acts as a tumor suppressor gene....

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מידע ביבליוגרפי
Main Authors: Laviolette, Laura A., Wilson, Jonas, Koller, Julia, Neil, Christopher, Hulick, Peter, Rejtar, Tomas, Karger, Barry, Teh, Bin Tean, Iliopoulos, Othon
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708955/
https://ncbi.nlm.nih.gov/pubmed/23874397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066775
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