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Eccrine Sweat Contains IL-1α, IL-1β and IL-31 and Activates Epidermal Keratinocytes as a Danger Signal

Eccrine sweat is secreted onto the skin's surface and is not harmful to normal skin, but can exacerbate eczematous lesions in atopic dermatitis. Although eccrine sweat contains a number of minerals, proteins, and proteolytic enzymes, how it causes skin inflammation is not clear. We hypothesized...

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Bibliographic Details
Main Authors: Dai, Xiuju, Okazaki, Hidenori, Hanakawa, Yasushi, Murakami, Masamoto, Tohyama, Mikiko, Shirakata, Yuji, Sayama, Koji
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708933/
https://ncbi.nlm.nih.gov/pubmed/23874436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067666
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