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Assessment of Motor Function, Sensory Motor Gating and Recognition Memory in a Novel BACHD Transgenic Rat Model for Huntington Disease

RATIONALE: Huntington disease (HD) is frequently first diagnosed by the appearance of motor symptoms; the diagnosis is subsequently confirmed by the presence of expanded CAG repeats (> 35) in the HUNTINGTIN (HTT) gene. A BACHD rat model for HD carrying the human full length mutated HTT with 97 CA...

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書誌詳細
主要な著者: Abada, Yah-se K., Nguyen, Huu Phuc, Schreiber, Rudy, Ellenbroek, Bart
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708912/
https://ncbi.nlm.nih.gov/pubmed/23874679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068584
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