The HCMV gH/gL/UL128-131 Complex Triggers the Specific Cellular Activation Required for Efficient Viral Internalization into Target Monocytes

We have established that HCMV acts as a specific ligand engaging and activating cellular integrins on monocytes. As a result, integrin signaling via Src activation leads to the functional activation of paxillin required for efficient viral entry and for the biological changes in monocytes needed for...

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Detaylı Bibliyografya
Asıl Yazarlar: Nogalski, Maciej T., Chan, Gary C. T., Stevenson, Emily V., Collins-McMillen, Donna K., Yurochko, Andrew D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708883/
https://ncbi.nlm.nih.gov/pubmed/23853586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003463
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