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Targeting Iron Acquisition Blocks Infection with the Fungal Pathogens Aspergillus fumigatus and Fusarium oxysporum

Filamentous fungi are an important cause of pulmonary and systemic morbidity and mortality, and also cause corneal blindness and visual impairment worldwide. Utilizing in vitro neutrophil killing assays and a model of fungal infection of the cornea, we demonstrated that Dectin-1 dependent IL-6 produ...

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Main Authors: Leal, Sixto M., Roy, Sanhita, Vareechon, Chairut, Carrion, Steven deJesus, Clark, Heather, Lopez-Berges, Manuel S., diPietro, Antonio, Schrettl, Marcus, Beckmann, Nicola, Redl, Bernhard, Haas, Hubertus, Pearlman, Eric
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708856/
https://ncbi.nlm.nih.gov/pubmed/23853581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003436
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