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Iron homeostasis—Achilles’ heel of Aspergillus fumigatus?
The opportunistic fungal pathogen Aspergillus fumigatus adapts to iron limitation by upregulation of iron uptake mechanisms including siderophore biosynthesis and downregulation of iron-consuming pathways to spare iron. These metabolic changes depend mainly on the transcription factor HapX. Consiste...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Current Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162135/ https://ncbi.nlm.nih.gov/pubmed/21724450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2011.06.002 |
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