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Cathelicidin-like Helminth Defence Molecules (HDMs): Absence of Cytotoxic, Anti-microbial and Anti-protozoan Activities Imply a Specific Adaptation to Immune Modulation

Host defence peptides (HDPs) are expressed throughout the animal and plant kingdoms. They have multifunctional roles in the defence against infectious agents of mammals, possessing both bactericidal and immune-modulatory activities. We have identified a novel family of molecules secreted by helminth...

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Autores principales: Thivierge, Karine, Cotton, Sophie, Schaefer, Deborah A., Riggs, Michael W., To, Joyce, Lund, Maria E., Robinson, Mark W., Dalton, John P., Donnelly, Sheila M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708846/
https://ncbi.nlm.nih.gov/pubmed/23875042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002307
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