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Cathelicidin-like Helminth Defence Molecules (HDMs): Absence of Cytotoxic, Anti-microbial and Anti-protozoan Activities Imply a Specific Adaptation to Immune Modulation

Host defence peptides (HDPs) are expressed throughout the animal and plant kingdoms. They have multifunctional roles in the defence against infectious agents of mammals, possessing both bactericidal and immune-modulatory activities. We have identified a novel family of molecules secreted by helminth...

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Bibliografske podrobnosti
Main Authors: Thivierge, Karine, Cotton, Sophie, Schaefer, Deborah A., Riggs, Michael W., To, Joyce, Lund, Maria E., Robinson, Mark W., Dalton, John P., Donnelly, Sheila M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708846/
https://ncbi.nlm.nih.gov/pubmed/23875042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002307
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