Genome-scale Co-evolutionary Inference Identifies Functions and Clients of Bacterial Hsp90

The molecular chaperone Hsp90 is essential in eukaryotes, in which it facilitates the folding of developmental regulators and signal transduction proteins known as Hsp90 clients. In contrast, Hsp90 is not essential in bacteria, and a broad characterization of its molecular and organismal function is...

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Bibliographic Details
Main Authors: Press, Maximilian O., Li, Hui, Creanza, Nicole, Kramer, Günter, Queitsch, Christine, Sourjik, Victor, Borenstein, Elhanan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708813/
https://ncbi.nlm.nih.gov/pubmed/23874229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003631
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