Transcription-Factor-Mediated DNA Looping Probed by High-Resolution, Single-Molecule Imaging in Live E. coli Cells

DNA looping mediated by transcription factors plays critical roles in prokaryotic gene regulation. The “genetic switch” of bacteriophage λ determines whether a prophage stays incorporated in the E. coli chromosome or enters the lytic cycle of phage propagation and cell lysis. Past studies have shown...

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Bibliographic Details
Main Authors: Hensel, Zach, Weng, Xiaoli, Lagda, Arvin Cesar, Xiao, Jie
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708714/
https://ncbi.nlm.nih.gov/pubmed/23853547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001591
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