Baicalein Protects Against Retinal Ischemia by Antioxidation, Antiapoptosis, Downregulation of HIF-1α, VEGF, and MMP-9 and Upregulation of HO-1

PURPOSE: Retinal ischemia-associated ocular disorders are vision threatening. This study examined whether the flavonoid baicalein is able to protect against retinal ischemia/reperfusion. METHODS: Using rats, the intraocular pressure was raised to 120 mmHg for 60 min to induce retinal ischemia. In vi...

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Main Authors: Chao, Hsiao-Ming, Chuang, Min-Jay, Liu, Jorn-Hon, Liu, Xiao-Qian, Ho, Li-Kang, Pan, Wynn H.T., Zhang, Xiu-Mei, Liu, Chi-Ming, Tsai, Shen-Kou, Kong, Chi-Woon, Lee, Shou-Dong, Chen, Mi-Mi, Chao, Fang-Ping
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2013
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708628/
https://ncbi.nlm.nih.gov/pubmed/23537149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2012.0179
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