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Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer

BACKGROUND: Non-muscle invasive (NMI) bladder cancer is characterised by increased expression and activating mutations of FGFR3. We have previously investigated the role of microRNAs in bladder cancer and have shown that FGFR3 is a target of miR-100. In this study, we investigated the effects of hyp...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Blick, C, Ramachandran, A, Wigfield, S, McCormick, R, Jubb, A, Buffa, F M, Turley, H, Knowles, M A, Cranston, D, Catto, J, Harris, A L
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Publishing Group 2013
Θέματα:	Clinical Study
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3708569/ https://ncbi.nlm.nih.gov/pubmed/23778527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.240
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Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer

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